Pharmaconex is part of the Informa Markets Division of Informa PLC

Informa
Informa

ACTIVE PHARMACEUTICAL INGREDIENTS AND WHY THEY MATTER  

LOCAL API MANUFACTURERS  

Unless you have never taken a pharmaceutical drug in your life, then you have taken an Active Pharmaceutical Ingredient (API). All drugs are made up of two things: the major active ingredient which is the API and an excipient which is an inactive compound that can be thought of as a carrier component. APIs are found in both over-the-counter and prescription medication. In generic (non-name brand) medications, the name of the API is also the name of the product. For example, you might recognize acetaminophen as Paracetamol or diazepam as Valium. 

Some drugs, specifically combination therapies, include more than one API and have more than one intended health effect. It can be easy to confuse APIs for raw materials, but the main difference is that a raw material needs to be manufactured before it becomes an active and potent ingredient that can be used.  

APIs can be divided into two broad categories: synthetic APIs which are manufactured in labs, and natural APIs which are derived from biological sources, then purified to become usable APIs. APIs are also sometimes categorized based on solubility into soluble and insoluble APIs.  

APIs make it easier for pharmaceutical companies to manufacture drugs without having to start from scratch every time. It can be more profitable to outsource APIs to a different pharmaceutical company which specializes in the drug, which in turn helps companies allocate more resources to research and development. It also makes drugs more accessible to a wider public since costs come down because of economies of scale. A company that can manufacture an API at a large volume can offer it at lower prices, bringing down the cost of the final drug. This has helped improve healthcare and medicine availability in poorer countries that may not have otherwise been able to develop their own drugs. 

Locally, Egypt has a strong pharmaceutical industry with several large players that produce APIs, like Manapharm, Eipico, and SGS. The government has also been encouraging Indian API manufacturers to relocate or build production plants in the Suez Canal Economic Zone (SCZone). This would open up the market to the manufacturers, create jobs as well as control drug prices in Egypt. 

APIs are an integral cog in the machine of medicine manufacturing and have changed the way pharmaceutical companies develop and produce their drugs. Their use will only increase as the future unfolds, and scientists develop newer compounds and improve on existing ones.